Simulated Isotope Exchange Patterns Enable Protein Structure Determination
نویسندگان
چکیده
منابع مشابه
Selectively dispersed isotope labeling for protein structure determination by magic angle spinning NMR.
The power of nuclear magnetic resonance spectroscopy derives from its site-specific access to chemical, structural and dynamic information. However, the corresponding multiplicity of interactions can be difficult to tease apart. Complimentary approaches involve spectral editing on the one hand and selective isotope substitution on the other. Here we present a new "redox" approach to the latter:...
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2017
ISSN: 0044-8249
DOI: 10.1002/ange.201704604